EM-T2Ecotoxicology and Environmental Safety2025-03-01第 292 卷，117964-117964开放获取高影响力 · 前 10%

Perfluorooctane sulfonate mediates GSH degradation leading to oral keratinocytes ferroptosis and mucositis through activation of the ER stress-ATF4-CHAC1 axis

Ningning YangFirst Affiliated Hospital of Wenzhou Medical University
Kemin JiaRuian People's Hospital
Kaixi DaiRuian People's Hospital
Qifang Wu Wenzhou University
Huanjuan YanWenzhou University
Haibin Tong Wenzhou University
Ya Zhang First Affiliated Hospital of Wenzhou Medical University
Xia Shao First Affiliated Hospital of Wenzhou Medical University

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关键词

PFOS ferroptosis oral mucositis oral keratinocytes glutathione depletion CHAC1 ATF4 endoplasmic reticulum stress lipid peroxidation GPX4 tauroursodeoxycholic acid persistent organic pollutants oxidative stress cysteinylglycine

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Ecotoxicology and Environmental SafetyElsevier

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引用这篇

YANG N, JIA K, DAI K, et al. Perfluorooctane sulfonate mediates GSH degradation leading to oral keratinocytes ferroptosis and mucositis through activation of the ER stress-ATF4-CHAC1 axis[J]. Ecotoxicology and Environmental Safety, 2025, 292: 117964-117964. DOI:10.1016/j.ecoenv.2025.117964.

著录项

学科: 工学环境科学与工程环境化学
类型: 研究论文
期刊: Ecotoxicology and Environmental Safety
卷期页: 第 292 卷，117964-117964
出版: 2025-03-01
语言: 英语
DOI: 10.1016/j.ecoenv.2025.117964

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